Physical Activity and Sleep SIG

SIG name

Physical Activity and Sleep

SIG leaders

List of local Investigators (name and affiliation)

  • Peter Eastwood, School of Human Sciences, UWA
  • David Hillman, Sir Charles Gardner Hospital, WA Sleep Disorders Research Institute
  • Romola Bucks, School of Psychological Science, UWA
  • Stewart King
  • Kath Maddison, School of Human Sciences, UWA
  • Jennifer Walsh, School of Human Sciences, UWA
  • Manon Dontje, Raine Study, UWA
  • Beth Hands, Institute for Health Research, Notre Dame University
  • Erin Howie, School of Physiotherapy & Exercise Science, Curtin University
  • Brennan Mils, School of Medical & Health Science, ECU
  • Leon Straker, School of Physiotherapy, Curtin University
  • Darren Beales, Pain Options, Curtin University
  • Rae-Chi Huang, TKI
  • Anne Smith, School of Physiotherapy, Curtin University
  • Floran Zepf, Pediatrics, UWA
  • Phillip Melton, GOHaD, UWA
  • Trevor Mori, School of Biomedical Sciences, UWA

Overview of the current data resources available in the SIG area

  • SLEEP

    Generation 2: (22 yr follow-up):

Sleep study (Laboratory PSG, n = 956)

Questionnaire: Sleep – Common sleep disorders (OSA, Insomnia, RLS), sleepiness, sleep behaviours (bed time etc), ‘morningness/eveningness’, accidents including motor vehicle

Actigraphy /sleep diary (1 week)

Generation 1:

Sleep study (Laboratory PSG, n = 948)

Detailed questionnaire data on medical history (doctor diagnosed conditions) and medications

Actigraphy /sleep diary (1 week)

  • ACTIVITY

Generation 2:

Sports participation (ages 5, 8, 10, 14, 17 and 20)

IPAQ (age 17, age 20, 22)

Pedometer & Multimedia Activity Recall for Children and Adolescents (MARCA) – age 14

Hip and Wrist Accelerometry (22 yr follow-up) (24hrs/day, 7 day week protocol) (Hip n = 774, Wrist n~800)

Generation 1:

Hip and Wrist Accelerometry (24hrs/day, 7 day week protocol) (Hip n ~ 1000, Wrist n~1000)

Generation 3:

Hip accelerometry (data currently being collected as part of Autism Biobank study, Gen 3- control arm)

Overview of current/recent SIG activity

  • SLEEP

Sleep data of Generation 2 (22 yr follow-up) is being analysed. Preliminary data indicates common sleep disorders are prevalent in young adults (OSA= 21%, insomnia =17% , restless legs         =3%),  phenotype of young adults with OSA: similar risk factors to middle age (male, obesity, snoring) but asymptomatic. Longitudinal predictors of sleep disorders will be sought.  Data              collection of Generation 1 has been completed recently, the sleep data is currently being cleaned and analysed.

  • ACTIVITY

The Sleep and Activity SIG is currently working on processing and analysing the actigraphy data of Generation 2. They are developing algorithms for raw accelerometry data, and are                    developing user friendly processing software for acceleromtery data. The algorithms and software will be further developed to analyse accelerometry data of Generation 1 and 3 as well.

Outline of SIG plans for next 5 years

  • SLEEP

The Sleep and Activity SIG will analyse prevalence, phenotype, associations between parental and offspring phenotype and discovery of genetic risk variants.  Generation 2 is currently                       undergoing a detailed assessment of cardiovascular health. The Sleep and Activity SIG will be assessing longitudinal relationships between sleep disorders and cardiovascular health.

  • ACTIVITY

The Sleep and Activity SIG will also be working on several other projects, such as:

  • Assessing correlates of physical activity and sedentary time
  • Using a compositional data analysis approach to assess accelerometer measured physical activity and sedentary behaviour and cardio-metabolic biomarkers
  • Comparing 4 methods including visual inspection, PSG, actigraphy algorithm, and diary data to analyze physical activity and sleep data
  • Identifying life course predictors of activity and inactivity
  • Processing wrist actigraphy data
  • Processing and analyzing actigraphy data of Generation 1 and 3

Brief list of potential student/early career researcher projects

Please contact the Physical activity and Sleep SIG Leaders if you are interested in a research project incorporating Physical activity and Sleep data and they will coordinate whom to contact within the group.

List of National/International Collaborating Investigators (name and affiliation)

Pending

Top 5-10 key findings (with reference)

  • SLEEP

    – There were strong associations found between reported musculoskeletal pain and restless legs syndrome in young adults.  (Hoogwout SJ, Paananen MV, Smith AJ, Beales DJ, O’Sullivan PB, Straker LM, Eastwood PR, McArdle N, Champion D. Musculoskeletal pain is associated with restless legs syndrome in young adults. BMC musculoskeletal disorders 2015;16:294).

  • ACTIVITY                                                                                                                                                                                                                                                                     

     – A trajectory characterized by less than 14 h/week TV viewing across childhood and adolescence predicts lower body fat in young adulthood.  (McVeigh JA, Smith A,    Howie EK, Straker L. Trajectories of television watching from childhood to early adulthood and their association with body composition and mental health outcomes in young adults. PloS One 2016;11:e0152879.)

Trajectories characterized by participation in sports across childhood and adolescence predict better physical health in young adulthood.  (Howie EK, McVeigh JA,                 Smith AJ, Straker LM. Organized sport trajectories from childhood to adolescence and health associations. Med Sci Sports Exerc 2016;48:1331-39)-

         Higher screen time exposure in early childhood predicts lower physical activity and higher BMI in later childhood but not in adolescence.  (Hands BP, Chivers PT,               Parker HE, Beilin L, Kendall G, Larkin D. The associations between physical activity, screen time and weight from 6 to 14 yrs: The Raine Study. J Sci Med Sport 2011;14:397–403)

List of indicative recent publications

  • SLEEP

    – Hoogwout SJ, Paananen MV, Smith AJ, Beales DJ, O’Sullivan PB, Straker LM, Eastwood PR, McArdle N, Champion D. Musculoskeletal pain is associated with restless legs syndrome in young adults. BMC musculoskeletal disorders 2015;16:294.

  • ACTIVITY

    – McVeigh JA, Smith A, Howie EK, Straker L. Trajectories of television watching from childhood to early adulthood and their association with body composition and mental health outcomes in young adults. PloS One 2016;11:e0152879.

– Howie EK, McVeigh JA, Smith AJ, Straker LM. Organized sport trajectories from childhood to adolescence and health associations. Med Sci Sports Exerc 2016;48:1331-39

– Hands BP, Chivers PT, Parker HE, Beilin L, Kendall G, Larkin D. The associations between physical activity, screen time and weight from 6 to 14 yrs: The Raine Study. J Sci Med Sport                       2011;14:397–403)

– McVeigh JA, Zhu K, Mountain J, Pennell CE, Lye SJ, Walsh JP, Straker LM. Longitudinal trajectories of television watching across childhood and adolescence predict bone mass at age 20 in          the Raine Study. Journal of Bone and Mineral Research 2016 (31):2032-2040

– McVeigh JA, Winkler EAH, Howie EK, Tremblay MS, Smith A, Abbott RA, Eastwood PR, Healy GN, Straker LM. Objectively measured patterns of sedentary time and physical activity in                   young adults of the Raine study cohort. International Journal of Behaviour Nutrition and Physical Activity 2016 (24): doi: 10.1186/s12966-016-0363-0.

– McVeigh JA, Winkler E, Healy G, Slater L, Eastwood P, Straker L. Validity of an automated algorithm to identify waking and in-bed wear time in hip-worn accelerometer data collected with              a 24-hour wear protocol in young adults. Physiological Measurement 37: 1636-1652, 2016

List of current/recent grants

  • 2012-14: NHMRC PROJECT GRANT: Childhood obesity and its relationship to adult sleep disordered breathing CIA Eastwood PR, CIB Hillman DR, CIC Smith A, CID McArdle N, CIE Huang R-C
  • 2015-17: NHMRC Project grant APP1084947 Prevalence, phenotype and genotype of common sleep disorders. CIA – Professor Peter Eastwood, CIB – Professor David Hillman, CIC – Professor Eric Moses , CID – Doctor Nigel McArdle , CIE – Doctor Phillip Melton.
  • 2016-18: NHMRC APP1109057 Project grant Predicting Obstructive Sleep Apnoea using 3D Craniofacial Photography   A/Pr Ajmal Mian , Dr Nigel Mcardle ,  Prof David Hillman, Prof Peter Eastwood

Examples of recent media

“Children who watch lots of TV have weaker bones in adulthood”- released as a press release from Curtin based on (McVeigh JA, Zhu K, Mountain J, Pennell CE, Lye SJ, Walsh JP, Straker LM. Longitudinal trajectories of television watching across childhood and adolescence predict bone mass at age 20 in the Raine Study. Journal of Bone and Mineral Research 2016 (31):2032-2040)

Resulted in 10+ newspaper articles, 6 radio interviews and a slot in Today Tonight