Gastro-intestinal

Non-alcoholic fatty liver disease (NAFLD) is fatty infiltration of the liver which is not related to drinking too much alcohol. It is related to insulin resistance and the metabolic syndrome. Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The epidemiology and clinical features of non-alcoholic fatty liver disease (NAFLD) in adolescents are unknown. The Raine Gastro-intestinal group are determining the prevalence and significance of hepatic and gastroenterological conditions among adolescents. They aim to explore the environmental and genetic modifiers of NAFLD and the metabolic and cardiovascular significance of NAFLD.