Cardiovascular

Professor Lawrie Beilin
Dr Trevor Mori
Professor Lyle Palmer
Professor Nick de Klerk
Dr Rae Chi Huang

The Cardiovascular Research team are examining cardiovascular health and metabolic syndrome. Metabolic syndrome is where a group of risk factors for cardiovascular disease (heart conditions) and  precursors of type 2 diabetes occur together. These risk factors include high blood pressure,  abnormal lipids , abdominal obesity (excess body fat around the waist) and insulin resistance. Three or more of these factors are known as metabolic syndrome which increase the risk of cardiovascular disease and type 2 diabetes. The Raine Study provides comprehensive information on children from the womb to adolescence. This information will help find the ways in which pregnancy and subsequent childhood exposures (physical activity, diet, illnesses)  interact with social and environmental factors to affect the long term risk of adult obesity, premature diabetes or heart disease. The study will also provide a basis for future examination of the links between genes, environment and health. 'This group interracts closely with other teams studying this cohort  where interests overlap. 

1.  Huang R-C, Mori TA, Burke V, Newnham J, Stanley FJ, Landau LI, et al. Synergy Between Adiposity, Insulin Resistance, Metabolic Risk Factors, and Inflammation in Adolescents. Diabetes Care. 2009 April 1, 2009;32(4):695-701.

2. Beilin L, Huang RC. Childhood obesity, hypertension, the metabolic syndrome and adult cardiovascular disease. Clin Exp Pharmacol Physiol. 2008 Apr;35(4):409-11.
3. Beilin L, Huang R-C. Perinatal and childhood precursors of adult cardiovascular disease. Clin Exp Pharmacol Physiol. 2007;34(s1):S2-S4.
4. Huang RC, Burke V, Newnham JP, Stanley FJ, Kendall GE, Landau LI, et al. Perinatal and childhood origins of cardiovascular disease. Int J Obes. 2007;31(2):236-44.
5. Burke V, Beilin LJ, Simmer K, Oddy WH, Blake KV, Doherty D, et al. Predictors of body mass index and associations with cardiovascular risk factors in Australian children: a prospective cohort study. Int J Obes Relat Metab Disord. 2005 Jan;29(1):15-23.
6. Burke V, Beilin LJ, Simmer K, Oddy WH, Blake KV, Doherty D, et al. Breastfeeding and overweight: longitudinal analysis in an Australian birth cohort. J Pediatr. 2005 Jul;147(1):56-61.
7. Burke V, Beilin LJ, Blake KV, Doherty D, Kendall GE, Newnham JP, et al. Indicators of fetal growth do not independently predict blood pressure in 8-year-old Australians - A prospective cohort study. Hypertension. 2004 Feb;43(2):208-13.
8. Blake KV, Gurrin LC, Beilin LJ, Stanley FJ, Kendall GE, Landau LI, et al. Prenatal ultrasound biometry related to subsequent blood pressure in childhood. J Epidemiol Commun H. 2002 SEP;56(9):713-8.
9. Blake KV, Gurrin LC, Beilin LJ, Stanley FJ, Landau LI, Newnham JP. Placental weight and placental ratio as predictors of later blood pressure in childhood. J Hypertens. 2001 APR;19(4):697-702.
10. Blake KV, Gurrin LC, Evans SF, Newnham JP, Landau LI, Stanley FJ, et al. Reference ranges for blood pressure in preschool Australians, obtained by oscillometry. J Paediatr Child H. 2000 FEB;36(1):41-6.
11. Blake KV, Gurrin LC, Evans SF, Beilin LJ, Landau LI, Stanley FJ, et al. Maternal cigarette smoking during pregnancy, low birth weight and subsequent blood pressure in early childhood. Early Human Development. 2000 FEB;57(2):137-47.
12. Blake KV, Gurrin LC, Evans SF, Newnham JP, Landau LI, Stanley FJ, et al. Reference ranges for blood pressure in preschool Australians, obtained by oscillometry. J Paediatr Child H. 2000 FEB;36(1):41-6.
13. Blake KV, Gurrin LC, Evans SF, Beilin LJ, Stanley FJ, Landau LI, et al. Adjustment for current weight and the relationship between birth weight and blood pressure in childhood. J Hypertens. 2000 AUG;18(8):1007-12.
14. Huang, R. C., Stanley, F. J. & Beilin, L. J. 2009, 'Childhood obesity in Australia remains a widespread health concern that warrants population-wide prevention programs', Medical Journal of Australia, vol. 191, no. 1, pp. 45-6.