What is the Raine Study?

The Raine Study started in 1989, when 2900 pregnant women were recruited into a research study at King Edward Memorial Hospital to examine ultrasound imaging. The mothers were assessed at 18 weeks of pregnancy, then some them again at 24, 28, 34 and 38 weeks of pregnancy. During this time information was collected on the mother and the father, for example diet, exercise, work, health, etc. After the children were born, they were assessed at birth, at one year, then two, three and five years of age. Information on their height, weight, eating, walking, talking, eating, behaviour, any medical conditions or illness etc was collected.

Further follow ups of the cohort have been conducted at eight, ten, fourteen, seventeen, twenty yearsof age.The current follow up is being done at 23 years of age. The Study Cohort are now 'adults' are being assessed without parents. We are very grateful to the parents of the Raine Cohort for their support and contribution to the Study over the years, and we welcome your continued involvement.

The Raine Study Time line

 

1989 - 1991

The Formation of the Cohort

2,900 pregnant women volunteered to be part of the study at King Edward Memorial Hospital looking a prenatal ultrasound scans. They were 18 weeks pregnant. Some of the mothers  were followed up at 24, 28 and 38 weeks gestation. All the  families then continued with follow up assessments of their babies. 2868 babies remained with the study and were examined on the first or second day after birth by a child health nurse in King Edward Memorial Hospital.

1990 - 1994

Follow up of babies and toddlers 

One year old
Two years old
Three years old

The children were examined at one, two and three years of age to assess and record their Growth and Development. At three years of age children's height, weight, blood pressure, physical health and developmental progress were measured. Information on the parents was collected

    

1994-1996

Five year old follow up
Concentrating on

  • Asthma and Allergy
  • Child's health
  • growth and development
  • Asthma, eczema
  • Skin prick tests for allergy
  • Lung function tests

1996-1997
Eight year follow up
Cardiovascular Health

  • Health and development
  • Physical activity and fat intake
  • Physical exercise - blood pressure
  • Blood samples (child and parent)
 
  1997-2000

Ten year follow up
Developmental Health

  • Schooling
  • Language development
  • Behaviour, general health
  • Parent health and happiness
  • Information from teachers and parents about academic achievement and cognitive development.
 

February 2000

The Raine Study, formerly situated within the grounds of Princess Margaret Hospital, relocated to the new Telethon Institute for Child Health Research building.

 

Raine Study 10th birthday

On April 9, 2000, the Raine Study celebrated its tenth birthday with five thousand people the grounds of Perth Modern School and the Telethon Research Institute.

 

 

 

 

2002 Open Day

In October 2002 the Raine Study held an open day at the Institute for Raine Study Families

 

 

 

19 July  2002

Australian Prime Minister, the Hon. John Howard visited the Institute and met some of the Raine Study children.

 

 

2002 Raine Study Logo - By Eloise

"First I thought of Raine Study and drew a raindrop, next I wrote the letters R.S in the middle.  

Then mum told me about how I came into the study by the ultrasound research, that gave me the idea of a baby in the womb, so I readjusted the words to make it look like a baby in the womb, then I coloured it in with blues,"

 

2003-2006

Fourteen year follow-up
Data collection completed in May 2006

  • physical activity
  • physical fitness and motor competence
  • diet
  • cardiovascular health
  • back pain,
  • mental health
  • lung function test
  • stress test
  • skin prick test for allergies
  • height, weight, blood pressure
  • blood sample
  • blood pressure monitor

 

2006-2009

Sixteen/seventeen year follow up

  • physical activity
  • physical fitness and motor competence
  • diet and nutrition
  • cardiovascular health
  • back pain,
  • mental health
  • height, weight, blood pressure
  • blood sample
  • blood pressure monitor
  • cognitive test
  • risk taking
  • liver ultrasound

2008 -2010

Challenge-me Study

at 18 years

  • Measuring Stress sensitivity
  • Cortisol levels through blood or saliva sample

2010 - 2012
Twenty Year follow up!

  • Eye health Study - 12 different eye tests to establish eye health in 20 year olds
  • DEXA Scan - to establish bone density and body composition
  • FibroScan - measuring liver stiffness using new technology
  • Male Fertility Study  
   

2011

Raine Study 21st Birthday Celebration

An exhibition and celebration of 21 years of the Raine Study was held on Sunday 6 November, 2011 in the Government House Gardens to celebrate and acknowledge the Raine Study participants, their families and the achievements of Raine Study Research. The event was formally opened by His Excellency The Governor and Mrs McCusker. The event was attended by the Raine Study participants, their partners, parents and members of the Western Australian Research community. Exhibition displays were set up by the Raine Study Research groups and Raine Study Team and entertainment and food were available.

 
 

 2011 to 2013
23 year cohort assessment - Sleep and asthma study

The assessment of the cohort at age 23 started in March 2012. Participants are invited to spend the evening and sleep overnight in the UWA Centre for Sleep Science, a state of the art purpose built sleep research facility. 

A major focus of the 23 year follow up is sleep. Almost nothing is known about the characteristics of sleep in young adults (what is normal sleep?) or the presence of sleep disorders (is sleep apnea or snoring very common?). Most studies on sleep have focused on children and middle-aged and elderly adults. As well as providing new information on the sleep biology of young adults, the 23 year Raine follow up study will also represent the start, at a critical age between childhood and adulthood, of the first Australian “longitudinal sleep cohort”. The best way to comprehensively measure sleep is by a laboratory-based overnight sleep study. To do this UWA has recently built the Centre for Sleep Science, a new 5-bed sleep research and teaching facility located on its main campus.

 

Asthma affects approximately 10% of Australians so nearly all of us will know someone who has asthma. For most people their asthma can be well controlled and it has a minimal impact on their lives. However, for some asthma is a big problem with many visits to doctors and hospitals. Raine study participants have played a major role in improving our understanding of asthma in children and adolescents. The follow ups at 6 and 14 years had a big asthma focus. While many children grow out of their asthma, a significant number continue to have asthma as adults. Asthma is again the focus for the 23 year follow up and we hope to learn more about factors that contribute to the persistence of asthma throughout childhood and into early adult life as well as to try to understand why some young adults develop asthma.

 

 

 

  

  

  

  

 

   

 

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Last updated 2 October 2013